The utilization of HTS tools and methods in olefin polymerization catalysis represents our core competence. We have solid and proven experience in the application our tools and competence to the study of the a large variety of catalytic systems (from heterogenous ZN catalysts to single-site systems) for the synthesis of most type of olefin-based homo- and copolymers.
Our miniaturized, automated and fully integrated HTS workflow allows us to successfully study catalytic processes at mg-scale, allowing the testing of commercial as well as novel catalysts at sub-mg or nanomole levels. In turn, the throughput (up to 96 experiments/day!) and automation of our workflow guarantees highly reproducible results generated at a tremendous rate, representing an ideal solution to address multivariate R&D needs and reduce time-to-market for catalyst and/or product development.
The workflow is centered around two PPR-48 platforms, well-established HTS platforms to carry out olefin polymerization experiments in slurry or solution conditions and semi-batch mode, with the main gaseous monomer fed on-demand based on an accurate pressure control.
More in details, each PPR-48 consists of 48 mini-reactors (“cells”) grouped in 6 arrays (“modules”) of 8 cells. Each cell has an operational volume of 5 mL and allows a polymer yield up to 200mg, with on-line monitoring of the main polymerization parameters (T, P and monomer conversion rate). The chemical and process conditions can be individually set for each cell, with the only restriction of single temperature and total pressure values for a given module.
The two PPR-48 polymerization platforms are integrated with our polymer characterization techniques (GPC, NMR and CEF), for which more details are available here.
Catalyst lead finding under fixed or variable conditions
Accurate evaluation of the catalyst performance (activity, comonomer affinity, hydrogen sensitivity, etc.)
Kinetic analysis based on on-line monomer conversion curves
Process optimization (temperature, pressure and activation conditions) steering on catalyst- or polymer properties
Preparation and characterization of innovative PO-based materials (e.g. olefin block copolymers, copolymers containing bulky olefins, terpolymers, copolymers of ethylene or propylene with functionalized monomers)